MaSARM Ane Mhedzisiro?
Ehe, maSARM ane runyorwa runoshamisa rwezvakanaka. Nekudaro, panogona kuve nemimwe mhedzisiro. Mubvunzo ndewokuti: iyo njodzi inosangana nemubairo here?
Selective Androgen Receptor Modulators, ayo anoonekwa seakachengeteka dzimwe nzira kune vanabolic steroid, vane mugove wavo wekukakavadzana senge imwe mimwe mishonga pasi rino. Pakave nezvakawanda zvataurwa, kunyanya pasocial media, kuti maSARM haana kuchengetedzeka sezvakataurwa. Vamwe vakatomboenderera mberi vachiti maSARM mhedzisiro akanyanya se steroid mhedzisiro.
Mubvunzo wekuti maSARM akakukoshera iwe ndeumwe chete iwe waunogona kupindura. Pamusoro peizvi, zvinofanirwa kugara zvichishandiswa nemvumo yepamberi neyekurapa. Ngatitsvagei chokwadi chiri kumashure kwezvakataurwa nemaSARM mhedzisiro, kuti iwe ugone kuenderera zvizere uine ruzivo.
Ndeapi angangoitika maSARM Mhedzisiro?
Sarudzo Androgen Receptor Modulators akagadzirwa semishonga yekusimudzira mutambo. Aya makomponi anovandudza kurovedza muviri, kusimba, kutsungirira, kugona kwemitambo, uye kuwedzera mhasuru nekuteedzera mhedzisiro ye testosterone.
Zvisinei, mumwe 2017 kudzidza rakaburitswa muRondedzero yeAmerican Medical Association yakaburitsa kuti zvigadzirwa zvakawanda zvinotengeswa online seSARMs zvine zvinhu zvisina kutenderwa, anabolic steroid, uye mahormone.
Chikamu chakaipisisa ndechekuti mazhinji ezvigadzirwa izvi ane zvinyorwa zvainyengera zvachose. Hazvishamisi kuti kuwedzeredza, kushungurudza, kana kunyangwe iko kushandiswa kwese kweaya maSARM kunoguma nemhedzisiro zvakanyanya senge iyo steroids.
Pachidzidzo ichi, vaongorori vakaongorora mishonga makumi mana nemana yakatengeswa nekutengeswa seSelection Androgen Receptor Modulators, vachishandisa nzira dzekuyedza sezvakatumirwa neWorld Anti-Doping Agency (WADA). Maitiro aya akaona zvinhu zvakarambidzwa weti uye sampuli yeropa yevatambi.
Yakawanikwa kuti yakawanda se39% yezvakaedzwa zvinowedzerwa zvaisanganisira mishonga isingatenderwe senge anabolic steroid uye inorambidzwa kukura mahormone. Kuita kuti zvinhu zviwedzere kuipa, 25% yezvakaedzwa zvinowedzerwa zvaisanganisira zvinhu zvakafanana izvo zvisina kana kumbotaurwa nezvazvo pama Labels.
Zvakare, mune makumi mashanu neshanu ezviitiko, huwandu hwemakemikari akanyorwa akange akasiyana zvakanyanya neakaratidzwa nekuongorora. Pakupedzisira, izvi zvinotsausa uye zvine njodzi zvakanyanya: MaSARM ekuwedzeredza anogona kuuraya.
Iwo anotevera makomponi akanyorwa pane iwo mavara:
- Andarine (inozivikanwawo seS-4 uye GTx-007);
- Cardarine (anonziwo Endurobol, GSK-516, GW1515, uye GW501516);
- Ibutamoren (anozivikanwa saMK-677 uye L-163191);
- Ligandrol (LGD-4033);
- Ostarine (inozivikanwawo seEnobosarm, GTx-024, MK-2866, uye S-22);
- Stenabolic (SR9009);
- Testolone (RAD-140).
Mumwe co-munyori wechidzidzo aive Shalender Bhasin, MB, BS, Muzvinafundo weMishonga paHarvard Medical School uye director wechirongwa chekutsvaga muhutano hwevanhurume paBrigham neWomen Hospital. Bhasin akataura kuti makemikari akawanikwa mukuongorora kwavo haana kubvumidzwa neUnited States Chikafu neDrug Administration (FDA).
Bhasin akawedzera kuti hapana zvishoma kune ruzivo nezve kushanda pamwe nekuchengetedzeka kwezvinhu izvi zvigadzirwa, nekuti makomponi aive asina kubvumidzwa. Izvo zvakaburitswa zvakare kuti mamwe emakomponi aya haana kumbobvira adzidzwa muvanhu.
Hazvishamise kuti iyo FDA yakaburitsa chirevo chekuyambira mushure meizvi nezve zvigadzirwa zvine Selective Androgen Receptor Modulators.
Vakacherekedza kuita kwekutyisidzira hupenyu - kusanganisira asi kusingagumi kune huturu hwechiropa - kwakacherechedzwa muvanhu vari kushandisa maSARM. Zvisinei, chidzidzo chacho chakacherechedzawo kuti zvakawanikwa hazvimiriri izvozvi zvigadzirwa zvine Selective Androgen Receptor Modulators, uye kuti mumwe mutemo unodiwa.
Kutengeswa kwepasi pevhu uye kushandiswa kwemaSARM kwakaita kuti makomponi ave nemakakatanwa, zvisinei mishonga iyi inogona rimwe zuva kushanda mhinduro yakakosha uye chinangwa chevarwere vazhinji nevatambi zvakafanana.
Kuenderera mberi nekutsvagisa nezve maSARM Mhedzisiro uye Kushandisa
Patricia Deuster, purofesa wezvechiuto uye zvekukurumidzira mushonga paUniiformed Services University yeHutano Sayenzi, akataura kuti Selective Androgen Receptor Modulators vanozivikanwa zvakanyanya pakati pemasoja sezvo ari nyore kutenga uye kuwana kupfuura anabolic-androgenic steroids.
Thomas O'Connor, munyori webhuku iri America paSteroid, akataura kuti vazhinji vevarwere vake vashandisi vevanabolic-androgenic steroids avo vakatendeukira kumaSARM nekuti makomputa aya aive asiri-chepfu. O'Connor akawedzerawo mubhuku rake kuti mazana - pamwe anopfuura 1000 - varwere vanobva kunzvimbo dzese dzehupenyu kubvira 2010 (kusanganisira vevadziviriri, mapurisa, vatambi vane simba, maakaunzi, nevamwe) vanga vachishandisa maSARM.
Dr. O'Connor akawedzera kuti zvinonetsa kuongorora kunyatsoitika kweSelection Androgen Receptor Modulators sezviri kushandiswa parizvino, sezvo vanhu vazhinji vachivasanganisa nemishonga yekuwedzera, mimwe mishonga, kana zvinhu zvakarambidzwa. Icho chokwadi chekuti vamwe vevashandisi ava vakawana mhedzisiro inogona kana isingareve kuti maSARM ane mhosva. Saizvozvowo, maSARM ekuwedzeredza anogona kunge ari kutamba.
Izvi hazvisi kutonga kunze kwekuti madhiragi aya akasununguka zvachose kune chero mapfupi- kana marefu-marefu mhedzisiro: zvisinei, nyanzvi dzinoratidza kuti icho chinhu chinofanirwa kuongororwa kweanotevera makore anouya.
Kudzivirira maSARM asina kuchengeteka uye maSARM Mhedzisiro
Ndeapi maSARM eMhedzisiro uye Ndingaite Sei Kuderedza Njodzi Yangu?
Wakambozvibvunza kuti chii chakaunza kunyadziswa kumaSARM? Vagadziri vane hutsinye varipo kunze uko, vasingazeze kukanganisa hutano hwako nehupenyu neakaderera- kana epamusoro-dosi makomputa, uye kunyangwe kushandisa macomputer anokuvadza.
Kana iwe uri kuzvibvunza pachako, "Ndeapi maSARMs mhedzisiro?", Iwe unofanirwa kuziva kuti ruzhinji rwemhedzisiro rinouya kubva kune vasina kutendeka zvigadzirwa. Nepo njodzi dzacho dzichideredzwa nekuongororwa, kushandiswa kwakabvumidzwa, mhedzisiro yakaipa inogona kuitika senge chero nemushonga.
Iyo poindi ndeyekuti: iko kukanganisa pano hakurere nemaSARM, asi nezvitoro zvisina tsarukano zvinoshanda mazviri. Genuine Selective Androgen Receptor Modulators vachiri muchikamu chekutanga chekutsvaga, asi vanoonekwa sevakachengeteka zvakakwana kune varapi pasirese.
Iko hakuna zvachose kuramba chokwadi chekuti kunyepera, pasi-dosed, uye yakanyanyisa-dosed mishonga inotungamira kumaSARM mhedzisiro. Uyezve, kushandiswa kweyechokwadi maSARM kunogona kutungamira kumhedzisiro, kunyanya kana mushandisi aine hypersensitivity iripo kune chero zvigadzirwa zvacho. Ichi ndicho chikonzero chikonzero nei kurapwa kwekutanga kusati kwagara kuchikurudzirwa kune chero munhu anoda kushandisa aya makemikari ane simba.
Munguva pfupi yapfuura, mitambo inodzora mitambo senge World Anti-Doping Agency (WADA), United States Anti-Doping Agency (USADA) uye International Olimpiki Committee vakaisa maSARM pasi pezita remishonga inosimudzira -kuita.
Izvi zvaive zvechikonzero chiri nyore chekuti maSARM anowedzera mashandiro emitambo uye anotendera vatambi, vanoshambira, mabhasikoro, magetsi, uye makiriketi kuwana mukana wakasarudzika pamusoro pevamwe. Mune yehunyanzvi kana yemakwikwi mamiriro, hongu izvi hazvigamuchirwe.
Mazita makuru saArizona Wildcats anochengetedza Allonzo Trier, murwi weUFC Jimmy Wallheads, mutambi weCrossFit Mitambo Ricky Garard, murwi weUFC Tim Means, naJosée SArda, vakakunda Masters Women 50-54 Division, vabatwa vachiita doping nemaSARM. Quentin Weber, mutambi wemagetsi, akasungirwa kushandisa S-22, inorambidzwa anabolic mumiririri. Anis Ananenka akarambidzwa kushandisa GW-501516. Chinyorwa chinoramba chichienderera mberi.
Sei maSARM Akagadziriswa?
Munguva yakapfuura, anabolic-androgenic steroid senge testosterone yaishandiswa nevatambi vekutandara, vatambi vehuremu, uye vamwe kuitira kuti vawane mhasuru, kurasikirwa nemafuta emuviri, uyezve kuita musimba.
Nekudaro, kwavo kushandisa kwaizivikanwawo neakanyanya steroid mhedzisiro mhedzisiro. Izvi zvakajeka kupfuura zvinobatsira zvevanabolic steroid.
Izvi zvaingova zvimwe zvezvikonzero maSARM akagadzirwa nemasayendisiti nemakambani emishonga kuti asarudze akananga mhasuru uye mamwe matishu kuti aderedze mamwe emhedzisiro yesteroid. Izvi zvakajekeswa nezvidzidzo uye miedzo inoratidza kuti kushandiswa kwemaSARM kunogona kupa zororo rinoshamisa kuvarwere vari kunetseka nekuvhiyiwa kwechiuno, gomarara, multiple sclerosis, kusagadzikana kweurinary, uye mhasuru dzisina simba dzechiuno.
Semuenzaniso, yakaratidzirwa nevhiki nhatu kutongwa kuBoston University iyo LGD-4033, inozivikanwawo seLigandrol, yaibvumika uye yakachengeteka muvarume vane hutano kana zvasvika pakuburitsa kunoshamisa mukusimba uye mhasuru pasina kusimudza njodzi yekenza yeprostate.
Izvo zvakakosha zvakanyanya kuti uzive kuti maSARM anofanirwa kungotengwa kubva kune zviri pamutemo SARM Chitoro iyo inoshanda chete mune yechokwadi uye premium-mhando Sarudzo Androgen Receptor Modulators. Zvakare, kushandiswa kwemaSARM kunofanirwa kugara kuchitungamirwa nezano reanachiremba vanokwanisa mushure mekunyatsoongorora uye kunzwisisa kuongororwa nhoroondo dzezvokurapa uye nhoroondo.
Pamusoro peizvi, kushandiswa kwemaSARM kunofanirwa kungoitirwa zvepamutemo uye zvekurapa pasi pehunyanzvi kutariswa kwechiremba. Izvo zvakakoshawo kuti uzive kuti maSARM emuromo anosarudzika kune avo emvura (injekiseni) vamwe, nekuda kwechikonzero chiri nyore chekuti ivo vari nyore kudya uye vane yakanyanya bioavailability.
Zvakare, vashandisi vemuromo havafanirwe kutarisana nematambudziko ekusaziva pasi- kana kuwedzeredza maSARM. Ivo zvakare havatarisane nenjodzi yekuumbika kwekuputika, kurwadziwa kunzvimbo dzekubaiwa jekiseni, kugovana tsono, uye nenjodzi yakawedzera yekutapurirana-pabonde kana zvimwe zvirwere nekuda kwekugovana tsono.
Muchidimbu, hapana kuramba chokwadi chekuti kushungurudzwa kwechero mushonga kusanganisira maSARM kunogona kutungamira kumhedzisiro. Nekudaro, iwe unogona kudzora zvakanyanya njodzi yeSARMs mhedzisiro nekucherechedza chikamu chepamusoro chekutarisira uye kushingairira kunogona kuwanikwa nekujekesa kwekuziva kweakasiyana Selective Androgen Receptor Modulators. Izvi zvinokubatsira iwe kuramba uchiziva, uye mukusarudza akanakisa maSARM pamitengo inonzwisisika.