Nei Uchishandisa maSARM?
Sarudzo uyerogen receptor modulators (SARMs) zvinotengeswa sezvigadzirwa zvinoteedzera mhedzisiro ye testosterone senge anabolic androgenic steroids (AAS) asi isina zvinokanganisa mhedzisiro yesteroid. Chaizvoizvo, inosarudza uyerogen receptor modulators ndiwo makomputa anogona kukurudzira kana kudzvinyirira akakosha emuviri materu receptors ane mukana wekuvandudza mhedzisiro uye kudzora mhedzisiro zvinoenderana nemaitiro ekuita kwekomboni.
Sarudzo uyerogen receptor modulators anozivikanwa kwazvo pasimba rezvemitambo uye kuvaka muviri semakomputa anogona kuwedzera mapfupa, mhasuru, uye kurasikirwa kwemafuta pasina kuvhara iyo Hypothalamic-pituitary-gonadal axis (HPG axis) kana kuwedzera estrogen.
Mumakore mashoma apfuura, vatsvagiri pasirese vakaunza zvakawanda zvakawanikwa mumamiriro ekuvandudza kunyorera bioavailability uye kudzikisira huturu hwehutachiona hweaya anoita ekuvandudza mishonga. Izvo zvakakosha kuti urangarire kuti yakasarudzika uyerogengen receptor modulators anoita pane mamwe ma androgen receptors mumuviri anowanikwa mune dzinoverengeka dzakakomba nyama. Androgen receptors anowanikwa mune seminal vesicle, prostate, sweat gland, genitalia, testis, ovary, gastrointestinal vesicular masero, thyroid follicular maseru, huropi, chiropa,adrenal cortex, gland dzinodzikamisa, uye bvudzi follicles.
Sarudzo uyerogen receptor modulators haina kungogadzirirwa simba vatambi uye amateur & nyanzvi dzekuvaka muviri. Aya makomputa anobatsirawo kune vanhu vari kunetsekana nematambudziko ehutano senge mhasuru yekuparadza kusagadzikana, kukuvara kwemitambo, kushaya simba, tsandanyama atrophy nekuda kwekukwegura, uye kupisa kukuvara. Kunyangwe paine akawanda aripo madhiragi anogona kusimudzira hupenyu hwehupenyu uye nekupa zororo kubva kune kunetseka kwehutano, maSARM ane mamwe mabhenefiti akawedzerwa ekusava-anonhuwirira uye asiri-methylated nemuviri. Naizvozvo, anosarudza uyerogen receptor modulators haashandurwe kune mamwe anoshanda esrogen kana androgen makomponi.
Izvo zvakare hazvina chepfu kuchiropa uye hunhu uhwu hunovaita sarudzo yakanaka kune vanhu vari kutambura nezviropa zviripo kana kutarisana nenjodzi yekuwedzera kwehutachiona hwechiropa. Muchidimbu, kusarudza uyerogen receptor modulators anobatsira vese vanhu vane hutano pamwe nevanhu vane chirwere chisingaperi vari kutsvaga kusimudzira hupenyu hwehupenyu hwavo.
Imwe yemabhenefiti akakosha ekusarudza uyerogen receptor modulators kugona kwavo kwakasarudzika kwekudzivirira kana kudzikisira tsandanyama atrophy kana mhasuru dzikatadziswa mukukanda. Zviripachena, idzi inhau dzakanaka dzevatambi uye vavaki vemuviri vanoshanda vasingaregi mukamuri yekurema, uye kumunda kusimudzira nekuchengetedza simba, mhasuru, kutsungirira, kusimba, uye simba sekusarudza uyerogen receptor modulators zvinokanganisa iyo nzira-yakaoma nzira kupora.
Mazhinji anosarudza uyerogen receptor modulators anokwanisa kukurudzira adenosine monophosphate-activated protein kinase (AMPK) inova nzira inosanganisirwa ne lipolysis uye mafuta oxidation. Testosterone-based compounds senge testosterone enanthate inoderedzawo mafuta uye inowedzera mhasuru asi maSARM, kusiyana nevanabolic steroid, haanyanye kudzvinyirira Follicle-inosimudzira mahormone (FSH) uye Luteinizing mahormone (LH) kunze kwekunge zvakanyanyisa kukwirisa madosi emakomputa aya. Izvi zvinonyatsoratidza kuti sarudzo uyerogen receptor modulators yakachengeteka munguva pfupi uyezve kwenguva yakareba kupfuura testosterone-yakatorwa steroidal makomponi.
Androgens ane mukana wekukwanisa kuwedzera kuumbwa kweperiosteal bone mu cortical bone nepo estrogen makemikari anoderedza kana kuderedza kuumbwa uku. Mune mazwi e-layman, androgens anobatsira mukuvaka compact, gobvu rekunze kwepfupa rinobatsira kushanda kwemuviri, kudzivirira nhengo, uye kuchengetedza calcium. Selective androgen receptor modulators zvakare inokwanisa kuderedza trabecular uye endocortical bone turnover. Zvakakosha kuyeuka pano kuti chiyero chepamusoro chekudzoka kwebhonzo chinowanzobatanidzwa nekuregererwa kwepfupa kurasikirwa iyo yakapfava, spongy, inoshanduka-shanduka, uye isina simba bhonzo inowanikwa pedyo nemajoini, pamagumo emapfupa akareba, uye mukati memukati we vertebrae.
Kuderedza kudzoka kwemapfupa uye kuwedzera kwemapfupa kunoratidza kuti Selective androgen receptor modulators isarudzo dzakanaka kune avo vanoonekwa kuti vane kana kuvandudza osteoporosis. Mune mamwe mazwi, Selective androgen receptor modulators ndiwo makomponi anoshamisa kune vanhu vari kutsvaga kudzikisa kutsemuka uye kusimbisa mapfupa.
MaSARM Uye Kuvaka Muviri
Sarudzo uyerogen receptor modulators anoshandiswa nema bodybuilders uye magetsi ekuwedzera kurasikirwa kwemafuta, kuwedzera mhasuru, uye kugadzirisa simba remuviri. Iyo inoshandiswa zvakare kugadzirisa kukuvara, kunatsiridza mhasuru uye pfupa simba, uye kusimudzira pfungwa yekugara zvakanaka. Vamwe vavaki vemuviri vanoshandisawo maSARM ari pakati pevanabolic steroid macircuit, prohormone macircuit, uye testosterone kutenderera kwe post kutenderera kurapa kana senzira dzakachengeteka kumakomponi aya.
Munguva yakapfuura, anabolic androgenic steroids uye prohormones zvakashandiswa kutonga nyika yekuvaka muviri. Asi izvi zvinoriumba zvine hukasha pamuviri uye zvinoshandiswa kukonzeresa kwakakomba mhedzisiro senge kukwirira kweropa, gomarara reprostate, acne, mhanza, gynecomastia, uye kudzikisira kunoshamisa mukugadzirwa kwe testosterone chaiyo. Izvi zvaingova zvimwe zvezvikonzero nei vavaki vemuviri uye magetsi vachisimudzira kuenda kumaSARM - nzira dzakachengeteka kune vanabolic steroid uye prohormones.
Akakurumbira maSARM
Zvino zvataverenga nezve Selective uyerogen receptor modulators, ngatiendei isu titarise kune akakurumbira maSARM, yavo dosing protocols, uye mhedzisiro yekuwana yakajeka uye yakazara nzwisiso ye maSARM anoshanda sei, mutsauko pakati peSARM, uye ayo maSARM anoteedzana zvakanaka pamwechete.
Tenga maSARM chaiwo kubva kune akanakisa MaSARM UK chitoro - Iyo SARM Chitoro.
Andarine (S-4)
Yemuromo isina steroidal SARM, Andarine inosarudzika-inosarudza Inosarudza uyerogen receptor modulator iyo ine mukana wekusimudzira mitezo yevanabolic mune yakakura hukuru kupfuura nhengo dze androgenic. Iko kushandiswa kweS-4 hakubatanidzwe nekuwedzera kwemazinga eestradiol. Izvo hazvinyanye kudzvinyirira Follicle-inosimudzira mahormone uye Luteinizing hormone. Izvi zvinoreva kuti Andarine anogona kuwedzera mapfupa uye mhasuru pasina kutungamira kune chero yakaipa mhedzisiro yeprostate.
Kunyanya kushandiswa kucheka kutenderera SARM, Andarine inoderedza lipoprotein lipase uye kuchengetwa kwemvura uku kuchiwedzera mhasuru. Izvi zvinoratidza zvakajeka kuti S-4 chinhu chinoshamisa chinowedzeredza kurasikirwa kwemafuta nepo ichiwedzera zvishoma kana kuchengetedza tsandanyama. Pamusoro pezvakanaka izvi, S-4 inoratidzawo kushanda kuburikidza nekuderedza njodzi yekutyoka kwemapfupa nekuchengetedza huwandu hwekupaza mapfupa padivi rezasi uye nekuwedzera simba remhasuru panguva imwe chete.
S-4 yakanakisa yakarongedzwa neGW-501516 uye MK-677. Tenga Andarine zvino!
Ostarine (MK-2866)
Ostarine, inozivikanwawo seOstabolic, iri SARM inosanganisirwa nekuvandudzwa kukuru mukushanda kwemuviri, kuonda kwemuviri, uye kunzwisisika kwe insulin. Munyika yekuvaka muviri, Ostarine inonyanya kuzivikanwa nezvayo mabhenefiti panguva yekubvongodza uye kugadzirisa zvikamu. MK-2866 mubatanidzwa unoshamisa nekuda kweyakagovanisa zvikamu zvekuvaka izvo zvinogona kubatsira vashandisi kurasikirwa nemafuta emuviri uye kuwana mhasuru panguva imwe chete.
Ostarine yakanyatso kuvezwa nemakomputa akaita seGW-501516, S-4, S-23, uye Testolone. Tenga Ostarine ikozvino kubva pakanakisa MaSARM UKchitoro - Iyo SARM Chitoro.
Zvigadzirwa zveLigandrol
Uyewo anozivikanwa se Anabolicum, LGD-4033 inoshamisa SARM yekucheka, kubhowa, kuwana simba, kana kudzosera zvikamu. Imwe yeSARM ine simba kwazvo, LGD-4033 inobatsira varimi vemuviri kuti vawane simba rakakura uye mhasuru yemahombekombe inogona kuchengetwa nyore uye kwenguva refu. Izvo zvakanakira kuvhara mabheji pakati pemasekonzi uye kunodzivirira kupera kwemapfupa. Iyi SARM ine kugona kubata kwakanyanya kushanda nekuwanda sekukatyamadza makumi mana kusvika makumi mashanu muzana inobvumidza vanhu kutarisira yakachena, yakaoma, uye inovandudza vascularity panguva yekucheka chikamu.
LGD-4033 yakanakisa yakarongedzwa neMK-2866, MK-677, uye S-4. Tenga LGD-4033 kubva ku SARM Chitoro- iyo yepasirose inonyanya kufarira shopu online yekutsvagisa giredhi maSARM.
S-23
Iyi yemumuromo isingawanikwe steroidal SARM inonyanya kuzivikanwa munyika yekuvaka muviri senge iri nani S-4 inosimudzira mhasuru kuomesa. Inozivikanwa se “Ivo Baba Vakuru”Yeanosarudza uyerogen receptor modulators, S-23 inokanganisa makemikari anogamuchira mumabhonzo uye mhasuru.
Kana ichibatanidzwa nekudya kwakanaka uye kushanda kwakanyanya, iyi SARM inobatsira vashandisi kuwana kwenguva refu uye zvisati zvamboitika mhasuru uremu uye kutsungirira kuwana. Nekushandisa iyi SARM kwenguva inosvika gumi kusvika gumi nemana mavhiki, vashandisi vanogona kutarisira kugadzirisa mafuta oxidisation, kuonda kwemhasuru, kusimba, kutsungirira, uye pfungwa yekugara zvakanaka.S-23inozivikanwa zvakare munyika yemitambo uye kusimudza simba seSARM ine simba inogona kunyatsogadzirisa catabolism mukarori yekushomeka uye zvinoshamisa kuvandudza mhasuru vascularity, kuomarara, uye kuomarara mazinga.
Cardarine (GW-501516)
Chiroto chekurota chekuvaka muviri, Cardarine (GW-501516) chinhu chakakurumbira uye chakabudirira mukomboni kana zvasvika pakubvisa mafuta asingadiwe. Kushandiswa kweiyi SARM kunoenderana nekuderedza kudzidziswa nguva yekudzosa uye kuwedzera kusimudza kutsungirira. Ese aya mabhenefiti anoshamisa anoita GW-501516 yakanakisa yekucheka kutenderera SARM iyo inogona kuvandudza mashandiro mune yekurovedza muviri ipfupi semavhiki masere kusvika gumi nemaviri.
Nekushandisa iyi Peroxisome proliferator-activated receptor-β agonist, vashandisi vanogona kutarisira kuvandudzwa kwesimba, kupisa mafuta, uye kurasikirwa kwemafuta. Zvakare, iyi SARM inopa chengetedzo isingaenzaniswi kumidziyo yeuropi kubva kukuvara kweiyo oxidative uye kushushikana nekusimudzira musero maseru kukura. Cardarine inonyanya kurongedzwa nemakomputa akaita seMK-2866, S-4, MK-677, uye Stenabolic.
Tenga Cardarine kubva kune inonyanya kufarirwa pasirese MaSARM UKchitoro - Iyo SARM Chitoro.